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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Nat Prod Rep. 2009 Mar 11;26(5):585–601. doi: 10.1039/b813799b

Scheme 8.

Scheme 8

Hoffmann's alternative Sonogashira cyclodimerization attempt. Reagents and conditions: PdCl2(PPh3)2, CuI, Et3N, DMF, or slow addition of 62 to PdCl2(PPh3)2, CuI, Et3N, THF.