Table 2.
Gene pathways as classified by KEGG that were significantly changed by exercise in early (11 pathways)- and late (6 pathways)-pubertal girls
| Pathway | No. of Genes |
P Value (EASE Score) | ||
|---|---|---|---|---|
| EG | LG | EG | LG | |
| Natural killer cell-mediated cytotoxicity | 22 | 18 | 2.8×10−4 | 1.8×10−5 |
| Antigen processing and presentation | 16 | 13 | 4.6×10−4 | 9.2×10−5 |
| B cell receptor signaling pathway | 14 | 10 | 5.7×10−4 | 1.3×10−3 |
| Type I diabetes mellitus | 9 | 7 | 5.6×10−3 | 4.9×10−3 |
| Hematopoietic cell lineage | 14 | 7.0×10−3 | NS | |
| Apoptosis | 12 | 9 | 3.7×10−2 | 2.2×10−2 |
| Adherens junction | 11 | 3.7×10−2 | NS | |
| Jak-STAT signaling pathway | 18 | 4.4×10−2 | NS | |
| Focal adhesion | 22 | 2.8×10−4 | NS | |
| Ubiquitin-mediated proteolysis | 16 | 4.6×10−4 | NS | |
| Glycan structures- biosynthesis 1 | 15 | 5.7×10−4 | NS | |
| Keratan sulfate biosynthesis | 9 | NS | 2.6×10−2 | |
EG, early-pubertal girls; LG, late-pubertal girls; KEGG, Kyoto Encyclopedia of Genes and Genomes; EASE, Expression Analysis Systematic Explorer; NS, not significant.