Skip to main content
. 2009 May 1;297(1):L35–L43. doi: 10.1152/ajplung.90399.2008

Fig. 6.

Fig. 6.

There is a reduction in HDAC2 activity with no global change in histone acetyltransferase (HAT) or HDAC activity levels in CFTR− cells. Enzymatic activity was assayed from nuclear extract using colorimetric activity assays. A: global HAT activity from nuclear extract samples. Cells were placed in serum-free medium 48 h before the preparation of nuclear extract. n = 6. B: global HDAC activity from nuclear extract samples. Cells were placed in serum-free medium 48 h before the preparation of nuclear extract. n = 6. C: deacetylase activity of immunoprecipitated HDAC2. No HDAC2 antibody (Ab) was used in 1 sample during the immunoprecipitation as a negative control. n = 3. *P < 0.004 for comparisons of CFTR+ with CFTR− cells. D: deacetylase activity of immunoprecipitated HDAC1. No HDAC1 antibody was used in 1 sample during the immunoprecipitation as a negative control. n = 3.