Table 1.

Evidence of atypical infection and immunological causes

Immunoglobulins

IgG 7.54 g/L (N 3.8–15.2 g/L)

IgA 2.62 g/L (N 0.64–2.58 g/L)

IgM 0.89 g/L (N 0.43–1.9 g/L)

IgE 9178 kU/L (N <70 kU/L)

Specific RAST to Aspergillus 16.7 kU/L Grade III response (N <0.35 kU/L)

Eosinophil count 1.95 ×109/l (N 0.04–0.4 ×109/L)

Complement function

C3 2.03 g/L (0.68–1.8 g/L)

C4 0.28 g/l (0.18–0.6 g/L)

CH100 – Normal

Alternate pathway – Normal

pANCA/cANCA – Negative

ASOT <200 units/ml (N <200 units/mL)

Neutrophil oxidative burst – Normal pattern

Nitroblue Tetrazolium test – <10 % unstimulated, >90% stimulated

Serology

Influenza A 1:32

Influenza B 1:64

Coxiella burnetti P2 <1:32

RSV 1:64

Mycoplasma pneumoniae <1:32

Adenovirus <1:32

Psitticosis/LGV <1:32

PCP culture – Negative

AFB culture – Negative