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. Author manuscript; available in PMC: 2009 Jul 16.
Published in final edited form as: Cell. 1994 Mar 25;76(6):989–999. doi: 10.1016/0092-8674(94)90377-8

Figure 6. Parvalbumin and Calbindin Expression.

Figure 6

Sections from P17 mice stained with parvalbumin (A–G) or calbindin-D28K (H and I) antibodies.

(A–C) Parvalbumin staining in the cerebral cortex.

(A) Somatosensory cortex from a wild-type mouse.

(B) The same area from a −/− mouse.

(C) Occipital visual cortex from a −/− mouse.

(D–G) Hippocampus sections from a +/+ mouse (D and F) and from a −/− mouse (E and G), documenting absence of neurons expressing parvalbumin in a −/− mouse. Abbreviations: ml, molecular layer; pl, pyramidal cell layer.

(H and I) Calbindin staining in the striatum (st) of +/+ (H) and −/− (I) mice, showing that the reduction is almost complete. Positive neurons between the globus pallidus (gp) and the striatum (arrows) appear the same.

Scale bars, (A–E) 200 μm; (F and G) 50 μm; (H and I) 200 μm.