Figure 4.

The 340-bp MERIII is sufficient for the pericentral activity of EIII in the adult liver. Livers were removed from 4-wk-old mice and stained with the anti-D^d antibody as described in Fig. 3. MERIII-βgl-D^d (A) and MERIII-EII-βgl-D^d (B), which contain the 340-bp MERIII element linked to βgl-D^d in the absence or presence of EII, respectively, exhibit pericentral staining that is restricted to one to two layers of cells.