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. Author manuscript; available in PMC: 2009 Jul 16.
Published in final edited form as: Eur Biophys J. 2008 May 27;37(8):1317–1328. doi: 10.1007/s00249-008-0338-4

Figure 3.

Figure 3

Calculated uptake of a monovalent weak base with log KOW = 2 and varying pKa from outside into cytosol, lysosomes and mitochondria; t = 1 h. a) Pd : Pn = α = 1; b) Pd : Pn = α = 0; “Lys default” is the simulation with the default ion membrane permeability of the model (Fig. 2), corresponding to α = 1 : 3162.