Table 1.
Baseline demographic and surgical characteristics
| All patients (n = 3098) | Patients with TEE (n = 46) | Patients with major bleeding (n = 62) | Patients with immunological event (n = 8) | |
| Age (years), mean ± SD | 60.7 ± 14.0 | 63.0 ± 10.0 | 58.6 ± 16.5 | 59.5 ± 11.8 |
| Gender (female/male), % | 43.7/56.3 | 28.3/71.7 | 32.3/67.7 | 37.5/62.5 |
| BMI (kg/m2), mean ± SD | 26.6 ± 4.9 | 27.2 ± 4.4 | 26.3 ± 6.1 | 26.0 ± 5.4 |
| Type of surgery, n (%): | ||||
| Hepatic | 1007 (32.5%) | 22 (47.8%) | 16 (25.8%) | 3 (37.5%) |
| Gastrointestinal | 500 (16.1%) | 7 (15.2%) | 13 (21.0%) | 2 (25.0%) |
| Urological | 422 (13.6%) | 2 (4.3%) | 6 (9.7%) | 1 (12.5%) |
| Vascular | 227 (7.3%) | 5 (10.9%) | 3 (4.8%) | 0 |
| Pulmonary | 224 (7.2%) | 4 (8.7%) | 6 (9.7%) | 1 (12.5%) |
| Cardiac | 173 (5.6%) | 0 | 5 (8.1%) | 1 (12.5%) |
| Gynaecological | 130 (4.2%) | 0 | 1 (1.6%) | 0 |
| Neurosurgical | 83 (2.7%) | 2 (4.3%) | 1 (1.6%) | 0 |
| Other | 424 (13.7%) | 4 (8.7%) | 10 (16.1%) | 0 |
| Indication for surgery, n (%): | ||||
| Primary malignancy | 1074 (34.7%) | 20 (43.5%) | 17 (27.4%) | 3 (37.5%) |
| Secondary malignancy | 619 (20.0%) | 12 (26.1%) | 7 (11.3%) | 3 (37.5%) |
| Benign neoplastic disease | 306 (9.9%) | 2 (4.3%) | 7 (11.3%) | 0 |
| Other | 1098 (35.4%) | 12 (26.1%) | 31 (50.0%) | 2 (25.0%) |
| Surgery, acute/elective, % | 10.2/89.8 | 10.9/89.1 | 24.2/75.8 | 12.5/87.5 |
| Duration of surgery (hours), mean ± SD | 3.2 ± 1.8 | 4.4 ± 2.4 | 3.7 ± 2.4 | 4.4 ± 2.8 |
| Patients receiving blood transfusion, n (%) | 892 (28.8%) | 14 (30.4%) | 31 (50.0%) | 2 (25.0%) |
| Number of transfusion units given, mean ± SD | 5.2 ± 7.3 | 9.5 ± 12.1 | 10.0 ± 15.9 | 3.5 ± 2.1 |
| Area of TachoSil used (cm2), mean ± SD | 53.7 ± 40.7 | 60.1 ± 41.4 | 51.7 ± 36.3 | 55.1 ± 40.8 |