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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Int J Geriatr Psychiatry. 2009 Aug;24(8):847–855. doi: 10.1002/gps.2206

Table 3. Post-hoc analyses (1).

MTHFR C/C vs. MTHFR C/T or T/T (dichotomized variable) COMT genotype as an ordinal variable

Left putamen
Predictor Beta F df p-value
Depressed/ Control −0.00013 0.71 1 0.4016
COMT −0.00004 0.04 1 0.8435
MTHFR −0.00021 0.10 1 0.7581
Depressed*COMT 0.00016 0.97 1 0.3249
Depressed*MTHFR 0.00052 2.69 1 0.1024
COMT*MTHFR 0.00017 0.84 1 0.3608
Depressed*COMT*MTHFR −0.00056 5.13 1 0.0244
Right putamen
Predictor Beta F df p-value
Depressed/ Control −0.00005 1.68 1 0.1965
COMT −0.00011 0.12 1 0.7282
MTHFR −0.00051 2.26 1 0.1338
Depressed*COMT 0.00013 2.89 1 0.0904
Depressed*MTHFR 0.00053 2.49 1 0.1161
COMT*MTHFR 0.00049 0.95 1 0.3305
Depressed*COMT*MTHFR −0.00071 7.19 1 0.0078

Age and sex were included as covariates