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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Int J Geriatr Psychiatry. 2009 Aug;24(8):847–855. doi: 10.1002/gps.2206

Table 4. Post-hoc analyses (2).

COMT Met/Met vs. COMT Val/Met or Val/Val (dichotomized variable) MTHFR genotype as an ordinal variable

Left putamen
Predictor Beta F df p-value
Depressed/ Control −0.00043 0.97 1 0.3268
COMT −0.00022 0.21 1 0.6441
MTHFR −0.00015 0.59 1 0.4424
Depressed*COMT 0.00058 3.95 1 0.0479
Depressed*MTHFR 0.00049 1.44 1 0.2320
COMT*MTHFR 0.00023 0.33 1 0.5686
Depressed*COMT*MTHFR −0.00063 4.28 1 0.0396
Right putamen
Predictor Beta F df p-value
Depressed/ Control −0.00038 0.64 1 0.4237
COMT −0.00038 0.60 1 0.4388
MTHFR −0.00018 0.59 1 0.4423
Depressed*COMT 0.00051 2.63 1 0.1062
Depressed*MTHFR 0.00038 0.77 1 0.3799
COMT*MTHFR 0.00035 0.49 1 0.4856
Depressed*COMT*MTHFR −0.00048 2.12 1 0.1462

Age and sex were included as covariates