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Antimalarial activity of thiophenyl- and benzenesulfonyl-dihydroartemisinin against chloroquine-resistance (FCR-3) and -sensitive P. falciparum (FCR-8)
a)5 & 6, 10α- and 10β-thiophenyl-dihydroartemisinins; 7 & 8, 10α- and 10β-benzenesulfonyl-dihydroartemisinins.
b)IC50 represents the drug concentration producing 50% inhibition of the growth of P. falciparum in drug-free control wells. IC50 values were obtained from plots of the growth-inhibition data.
