Table 5. Tools for GO-based semantic similarity measures.
| Tool | Format Available | Measures Implemented | Input Sizea | Annotation Types | Extras |
| FuSSiMeG | Web | Several | 2 | All | None |
| GOToolBox | Web | Several | Unlimited | Single | Representation, Clustering, Semantic retrieval |
| ProteInOn | Web | Several | 10 | All/manual | Protein interaction |
| G-SESAME | Web | Wang et al. [25] | 2 | All manual, Single manual | Clustering, Filter by species |
| FunSimMat | Web | Several | Unlimited | All | Filter by protein family, Filter by species |
| DynGO | Standalone | AVG(Resnik) | Unlimited | All ECs | Visualization, Browsing, Semantic retrieval |
| UTMGO | Standalone | Othman et al. [11] | NA | IEA/non-IEA | Semantic retrieval of terms |
| SemSim | R | Several | NA | all/non-IEA | Support for clustering, filter by species |
| GOvis | R | simLP+simUI | NA | All | Visualization |
| csbl.go | R | Several | NA | NA | Clustering |
a
Acceptable number of terms or gene products.