Table 1.
Patient characteristics by 12-month EIA result*
| Variables | Total N=273 |
EIA negative N=59 (21.6) |
EIA indeterminate N=131 (48.0) |
EIA positive N=83 (30.4) |
p-value** |
|---|---|---|---|---|---|
| Male | 144 (52.8) | 29 (49.2) | 72 (55.0) | 43 (51.8) | 0.53 |
| Gestational age, median weeks | 40 (39, 40) | 40 (39, 40) | 40 (39, 40) | 40 (39, 40) | 0.45 |
| Birthweight, median kg | 2.90 (2.60, 3.18) | 2.90 (2.60, 3.20) | 2.80 (2.60, 3.10) | 2.90 (2.70, 3.20) | 0.82 |
| Maternal age, median years | 24 (21, 26) | 24 (21, 26) | 24 (21, 27) | 24 (22, 26) | 0.30 |
| Maternal antenatal ARVs, median days | 5 (0, 273) | 1 (0, 56) | 7 (0, 90) | 14 (0, 273) | 0.15 |
| Maternal ARV regimen | |||||
| sdNVP | 85 (31.1) | 20 (33.9) | 41 (31.3) | 24 (28.9) | -- |
| AZT+3TC+NFV | 72 (26.4) | 11 (18.6) | 36 (27.5) | 25 (30.1) | |
| AZT+3TC | 55 (20.2) | 12 (20.3) | 25 (19.2) | 18 (21.7) | |
| Other | 18 (6.6) | 5 (8.5) | 7 (5.3) | 6 (7.2) | |
| None | 37 (13.6) | 9 (15.3) | 21 (16.0) | 7 (8.4) | |
| Unknown | 6 (2.2) | 2 (3.4) | 1 (0.8) | 3 (3.6) | |
| Maternal protease inhibitor-containing regimen*** | 75 (32.6) | 11 (22.9) | 37 (33.9) | 27 (37.0) | 0.11 |
| Infant postnatal antiretrovirals, median days | 1 (0, 28) | 1 (0, 28) | 1(0, 28) | 4 (0, 28) | 0.77 |
| Infant ARV regimen | |||||
| sdNVP | 136 (49.8) | 30 (50.9) | 67 (51.6) | 39 (47.0) | -- |
| AZT+sdNVP | 71 (26.0) | 14 (23.7) | 31 (23.7) | 26 (31.3) | |
| AZT+3TC | 39 (14.3) | 9 (15.3) | 18 (13.7) | 12 (14.5) | |
| Other | 9 (3.3) | 3 (5.1) | 4 (3.1) | 2 (2.4) | |
| None | 12 (4.4) | 1 (1.7) | 10 (7.6) | 1 (1.2) | |
| Unknown | 6 (2.2) | 2 (3.4) | 1 (0.8) | 3 (3.6) | |
| Weight Z score at 12 months, mean +/− SD | −0.14 +/− 1.01 | −0.20 +/− 0.95 | −0.10 +/− 1.09 | −0.14 +/− 0.93 | 0.57 |
| Height Z score at 12 months, mean +/− SD | −0.30 +/− 1.24 | −0.10 +/− 1.20 | −0.41 +/− 1.26 | −0.29 +/− 1.24 | 0.15 |
| Age at EIA seroconversion, median months | 18.30 (12.87, 18.40) | 12.20 (12.17, 12.23) | 18.33 (18.27, 18.40) | 18.40 (18.30, 18.97) | -- |
*
Results presented as N (%) or median (interquartile range), unless otherwise noted. Abbreviations: ARV=antiretroviral, EIA=HIV enzyme-linked immunoassay, SD=standard deviation.
**
Univariate analyses conducted between EIA-negative vs. EIA-indeterminate and EIA-positive patients
***
Percentages based on the denominator of mothers who received ARVs.