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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Int J Oncol. 2009 Aug;35(2):257–263.

Figure 3. Downregulation of MMP-2 causes the up regulation of APAF-1 and ErbB-2 in 5310 but not in 4910 human glioma xenograft cells in vivo.

Figure 3

Nude mice with pre-established intracranial human glioma tumors (4910 or 5310) were treated with Ad-MMP-2 by intracranial injections (1 or 10×106pfu). 10 days following Ad-MMP-2 administration the brains were harvested sectioned and immunoprobed for ErbB-2 and APAF-1 using appropriate HRP conjugated (for ErbB2) or TxRed conjugated (for APAF-1) secondary antibody.