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Recruitment of STAT3 into the promoter of the mouse Mn-SOD gene is diminished by ischemic reperfusion. A, B, Recruitment of STAT3 into the promoter of the mouse Mn-SOD gene in chromatin from sham-operated mouse cortices or from mouse cortices subjected to 3 h of reperfusion after MCAO was determined by ChIP analysis using mouse Mn-SOD promoter-specific pairs of primers spanning the STAT3 binding sites. IP, Immunoprecipitation; S, sham; IR, ischemic reperfusion.
