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Schematics of the four-state model. (A) The scheme of the GJ channel containing the fast gate in each hemichannel. (B) Illustration of a four-state model: 1), AoBo—both gates are open, 2), AcBo—gate A closed and gate B open, 3), AoBc—gate A open and gate B closed, and 4), AcBc—both gates closed. Ki (I = 1–4) are equilibrium constants.
