Table 1.

Main causes of secondary chronic idiopathic pseudo-obstruction and relative gut tissue that is predominantly involved

Underlying disease	Main causes
Diseases of central autonomic and enteric nervous systems	Stroke, encephalitis, calcification of basal ganglia, orthostatic hypotension, Von Recklinghausen, Hirschsprung
Immune-mediated and collagen diseases	Paraneoplastic (CNS neoplasms, lung microstoma, bronchial carcinoid, leyomyosarcomas), scleroderma, dermatomyositis, amyloidosis, Ehlers-Danlos, LES
Endocrine and metabolic diseases	Diabetes, hypothyroidism, hypoparathyroidism, phaeochromocytoma
Other	Iatrogenic (radiation enteritis, clonidine, phenothiazines, antidepressants, antiparkinsonians, antineoplastics, bronchodilators, anthraquinones) jejunal diverticulosis, chagas