Figure 6.

Search time τ_s for CT enzymes, for copy number n₀ = 30, electron flip rate F = 10⁵, and electron speed U = 1. The actual search time in seconds can be recovered by dividing by k_on, whose value is estimated in Table 1. (a) Search time as a function of initial guanine density g₀ and lesion electron reflectivity r. Parameters used were σ = 0.9 and η = 10⁻¹⁰. (b) Search time τ_s as a function of enzyme binding affinity σ and enzyme diffusivity along DNA, η. Parameters used were g₀ = 30 and r = 0.5.