Table 1.

The link between a putative precursor (p53 signature), STIC and pelvic serous cancer.

1. Predilection for the distal fallopian tube (fimbria)

2. Occurs in the setting of cellular DNA damage (γ‐H2AX+)

3. Target the tubal secretory cell (HMFG2+/BCL2+/p73(−)/LHS28(−)

4. Strong nuclear accumulation of p53

5. Ovarian cancer‐associated p53 mutations

6. Documented continuity between the p53 signature and STIC

7. Existence of intermediate forms with features of both p53 signature and STIC

8. Shared risk factors (low parity, older age of first birth)