Table 2.

Important research questions regarding early serous carcinogenesis.

1. Defining the risk factors for the p53 signature.

2. Reproducing the p53 signature and the tubal serous carcinogenic sequence in vitro.

3. Determining the frequency of occult tubal serous carcinoma in the general population.

4. Successful imaging or molecular‐based detection of early serous carcinomas prior to extra‐genital spread.