Table 4. Estimated Population Attributable Risk of Hypertension Associated with Uric Acid and Insulin.

Biomarker Level	% of Total Population	Model 2 OR	Adjusted Incidence Rate (per 1000 py)	Population Attributable Risk (per 1000 py)
Uric Acid (mg/dL)
3.0 (1.5-3.3)	25	1.0	14.6*	0.0
3.7 (3.4-3.9)	25	1.27	18.5	0.98
4.2 (4.0-4.5)	25	1.62	23.7	2.28
5.1 (4.6-8.8)	25	1.89	27.6	3.25
≥ 3.4				6.51
Insulin (μIU/mL)
2.0 (0.2-2.8)	25	1.0	14.6*	0.0
3.8 (2.9-4.6)	25	1.03	15.0	0.10
5.8 (4.7-7.0)	25	1.22	17.8	0.80
9.6 (7.1-128.8)	25	2.03	29.6	3.75
≥ 2.9				4.65

^*Baseline incidence rate is drawn from incidence rate of the parent cohort (Nurses' Health Study II).

Adjusted incidence rate is the baseline incidence rate multiplied by the adjusted relative risk (OR).

The population attributable risk is the difference between the adjusted incidence rate and the baseline incidence rate multiplied by the % of the population.

[6.51/(14.6+6.51)] = 30.8% of hypertension occurring in young women is associated with a uric acid ≥ 3.4 mg/dL.

[4.65/(14.6+4.65)] = 24.2% of hypertension occurring in young women is associated with an insulin ≥ 2.9 μIU/mL.