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. 2009 May 5;38(2):186–195. doi: 10.1152/physiolgenomics.90376.2008

Fig. 3.

Fig. 3.

Genome-wide location analysis of Foxa2 in adult liver. A: experimental paradigm for the ChIP-on-Chip assay (n = 4 for each group). B: USCS Genome Browser screenshot of Foxa2 binding at the Pxr (Nr1i2) promoter. The scores for each tile indicate that the binding site is located near the middle tile (score = 9.1), close to the evolutionarily conserved region. C: confirmation of 10 randomly chosen targets found by genome-wide location analysis by QPCR. D: analysis of functional categories overrepresented in gene set bound by Foxa2.