FIG. 2.
Transient events of GABA release from DA cells. A: current traces from an isolated DA cell body infused with 100 nM free Ca2+ in CsCl-based patch solution; holding potential was −60 mV. The cell exhibited inward current transients that were reversibly suppressed by bath application of SR95531 (20 μM), an antagonist at the GABAA receptor. Ba: examples of transient current events and (Bb) an averaged trace (n = 58). C: application of 1 mM GABA to the cell activated an inward current. Da: distribution of the amplitudes of the current events. The mean peak amplitude was 13.0 ± 5.5 pA (n = 61). Db: scattergram of the amplitude-rise time (10–90%) relationship. Dc: scattergram of amplitude half-width time relationship.