Figure 2.

Immunostaining of CSPGs (clone CS-56) in MMP-9 null and wild-type mice after spinal cord injury. At 14 d postinjury, CSPG immunoreactivity appears at the interface (arrowheads) between the lesion epicenter (asterisks) and the intact tissue in both wild-type and MMP-9 null mice (A, B; horizontal sections). The wild-type mouse displays stronger CSPG immunostaining than the MMP-9 null mouse particularly at 42 d postinjury (C, D; transverse sections). Scale bars: A, B, 100 μm; C, D, 250 μm.