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. Author manuscript; available in PMC: 2009 Jul 17.
Published in final edited form as: Graefes Arch Clin Exp Ophthalmol. 2008 Apr 11;246(7):1029–1046. doi: 10.1007/s00417-008-0805-8

Table 10.

Comparison of percent improvement in visual field defect* between those with initial moderate to severe visual field defect and were seen within 2 weeks of NA-AION onset who received steroid therapy within 2 weeks of onset and those that did not receive any steroid

Follow-up period Percent with improved visual field* (95% confidence interval)
Odds ratio (95% CI) for VF
improvement (steroid/no steroid)
p value
Steroid No steroid**
At ODE resolution 36.6% (29.7%, 43.9%) 19.6% (13.8%, 27.0%) 2.36 (1.41, 3.96) 0.001
3 months from first visit 37.7% (30.8%, 45.0%) 19.7% (13.9%, 27.2%) 2.47 (1.48, 4.12) 0.0006
6 months from first visit 40.1% (33.1%, 47.5%) 24.5% (17.7%, 32.9%) 2.06 (1.24, 3.40) 0.005
1 year from first visit 40.0% (33.0%, 47.3%) 24.7% (17.8%, 33.1%) 2.03 (1.23, 3.36) 0.006
*

Estimates obtained from the repeated measures logistic regression model fitted using the generalized estimating equations (GEE) method

**

From cohort of patients in our natural history study of NA-AION [28]

CI = Confidence interval; NA-AION = Non-arteritic anterior ischemic optic neuropathy; ODE = Optic disc edema; VF = Visual field