. Author manuscript; available in PMC: 2009 Jul 17.

Published in final edited form as: Graefes Arch Clin Exp Ophthalmol. 2008 Apr 11;246(7):1029–1046. doi: 10.1007/s00417-008-0805-8

Table 9.

Comparison of percent improvement in visual acuity^* among those with initial visual acuity of 20/70 of worse that were seen within 2 weeks on NA-AION onset who received steroid therapy within two weeks of onset and those that did not receive any steroid

Follow-up period	Percent with improved visual acuity^* (95% Confidence Interval)		Odds ratio (95% CI) for VA improvement (steroid/no steroid)	p value
	Steroid	No steroid^**	Odds ratio (95% CI) for VA improvement (steroid/no steroid)	p value
At ODE resolution	44.2% (33.1%, 56.0%)	21.2% (13.2%, 32.2%)	2.95 (1.42, 6.17)	0.004
3 months from first visit	47.1% (35.8%, 58.7%)	16.7% (9.6%, 27.3%)	4.45 (2.03, 9.75)	0.0002
6 months from first visit	69.8% (57.3%, 79.9%)	40.5% (29.2%, 52.9%)	3.39 (1.62, 7.11)	0.001
1 year from first visit	72.2% (60.2%, 81.6%)	39.0% (27.6%, 51.7%)	4.06 (1.92, 8.57)	0.0002

Estimates obtained from the repeated measures logistic regression model fitted using the generalized estimating equations (GEE) method

^**

From cohort of patients in our natural history study of NA-AION [28].

CI = Confidence interval; NA-AION = Non-arteritic anterior ischemic optic neuropathy; ODE = Optic disc edema; VA = Visual acuity