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Extracted ion chromatograms of selected metabolites obtained from microsomal incubates: ketamine (m/z 238), norketamine (m/z 224), hydroxynorketamine (m/z 240), tetradeuterated hydroxynorketamine (m/z 244), trideuterated hydroxynorketamine (m/z 243), hydroxyketamine (m/z 254), tetradeuterated hydroxyketamine (m/z 258), trideuterated hydroxyketamine (m/z 257), and dehydronorketamine (m/z 222). Dotted lines are drawn through the peaks discussed in the main text.
