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Chromatograms of a urine sample spiked with deuterated metabolites before extraction, showing isomers of hydroxynorketamine. a, superimposed chromatograms for the transitions m/z 240/125 and 244/129 for alcoholic hydroxynorketamine and hydroxynorketamine-d4 showing overlap at peaks 1 to 3 and 7. b, superimposed chromatograms for the transitions m/z 240/141 and 243/144 for phenolic hydroxynorketamine and hydroxynorketamine-d3 showing overlap at peaks 4 to 6.
