Table 1.

Case 1

Day following diagnosis	1	5	14	35	110	125	175
Serum Cu (80–100 mcg/dL)	4	43	105	101	101	116	127
Ceruloplasmin (21–53 mg/dl)	3	12	32	31	35	32	48
Reticulocyte count (0.020–0.076 106/mcL)	0.033	0.088	0.082	0.055	0.035
Hemoglobin (11.4–14.7 gm/dL)	9.5	9.4	13.2	12.5	10.1	11.1	11.1
Hematocrit (33.3–41.4 %)	28.7	28.6	41	38.7	31.3	34.3	33.7
WBC 103/mcL	1.3		12.6	6.0	6.1	5.9	8.7
Absolute neutrophil count (1500–8000 cells/uL)	592	490	10584	3420	3111	3481	6090
Form of copper administered	IV	IV	IV/PO	IV/PO	PO	PO	PO

Normal laboratory ranges in parenthesis.

IV = copper 2.4mg/day; IV/PO = copper 2.4mg IV/week and copper 8 mg po/day; PO = copper 8 mg po/day