Table 1.
Clinical features of ET cases who report embarrassment s vs. ET cases who do not report embarrassment
| ET cases who reported embarrassment (n = 203) | ET cases who did not report embarrassment (n = 146) | Significance (p value) | |
|---|---|---|---|
| Age in years | 65.5 ± 16.2 | 69.5 ± 13.8 | 0.02a |
| Female Gender | 115 (56.7%) | 63 (43.2%) | 0.01b OR = 1.7 (1.1 – 2.7) |
| White Race | 188 (92.6%) | 140 (95.9%) | 0.20b |
| Education (years) | 14.7 ± 3.8 | 15.5 ± 3.9 | 0.050a |
| Age of tremor onset in years | 40.8 ± 22.9 (n = 198) | 50.4 ± 20.8 | <0.001a |
| Tremor duration in years | 25.2 ± 18.9 (n = 198) | 19.1 ± 17.6 | 0.003a |
| First- or second-degree relative with ET or tremor | 138 (68.0%) | 80 (54.8%) | 0.01b OR = 1.8 (1.1 – 2.7) |
| Currently takes daily medication for tremor | 112 (55.2%) | 56 (38.4%) | 0.002b OR = 2.0 (1.3 – 3.1) |
| Total tremor score | 19.9 ± 7.5 | 17.4 ± 6.4 | 0.001a |
| Tremor disability scale score | 59.0 ± 28.6 (n = 202) | 41.1 ± 27.6 (n = 140) | <0.001a |
| Performance-based test score* | 34.3 ± 22.2 (n = 116) | 26.2 ± 19.3 (n = 75) | 0.01a |
| CIRS score | 5.6 ± 3.7 | 5.5 ± 3.6 (n = 141) | 0.76a |
| Head tremor by history | 78 (38.6%) (n = 202) | 44 (30.3%) (n = 145) | 0.11b OR = 1.4 (0.92 – 2.3) |
| Head tremor on exam | 83 (40.9%) | 50 (34.2%) | 0.21b |
| Voice tremor by history | 49 (24.1%) | 15 (10.3%) | 0.001b OR = 2.8 (1.5 – 5.2) |
| Voice tremor on exam | 71 (35.3%) (n = 201) | 38 (26.2%) (n = 145) | 0.07b OR = 1.5 (0.96 – 2.5) |
Values represent mean ± standard deviation or number (percentage). For some items, there were missing data and sample size is provided in parentheses (e.g., n = 198).
*
Performance-based test score was performed as part of a sub-study.
OR = odds ratio with 95% confidence intervals.
a
t test
b
Chi-square test
CIRS = Cumulative Illness Rating Scale.