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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Neuropsychologia. 2009 May 3;47(12):2470–2479. doi: 10.1016/j.neuropsychologia.2009.04.024

Table 3.

Location, Size, and Magnitude of MD Group Activations during the Approximate Calculation Task

Anatomical Region Talairach coordinates cluster size stat max (T) significance MD % sig. change1 TD % sig. change2 BA
X Y Z
LH cingulated gyrus −6 20 40 40281 9.97 0.001 0.3369 0.1864 32
RH frontal lobe 27 2 52 8310 9.37 0.001 0.3406 0.2354 6
 RH middle frontal gyrus* 45 29 25 46
 RH frontal lobe* 27 2 52 6
RH claustrum 30 14 4 2502 9.17 0.001 0.2382 0.0971 -
LH precuneus 0 −64 40 18991 8.87 0.001 0.4433 0.2324 7
LH precuneus −27 −64 34 11281 7.44 0.001 0.3239 0.2213 7
RH inferior parietal lobe 39 −52 43 6250 7.29 0.001 0.2743 0.2151 40
 RH precuneus* 30 −67 37 19
LH IFG/caudate body −15 −1 19 4519 7.14 0.001 0.1961 0.0250 -
 LH middle frontal gyrus* −33 17 28 9
 LH middle frontal gyrus* −30 44 16 10
 LH claustrum* −24 20 7 -
 LH inferior frontal gyrus* −39 38 7 46
RH middle frontal gyrus 24 41 −2 655 5.95 0.004 0.3815 0.0592 11
LH medial frontal gyrus −3 2 58 615 4.88 0.008 0.5003 −0.0074 6

cluster size in mm3

*

regions are local maxima within the larger cluster of activation

1

= the MD group’s activation for the approximation task versus symbol matching control

2

= the TD group’s activation for the approximation task versus symbol matching control