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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Spine (Phila Pa 1976). 2009 Apr 1;34(7):648–654. doi: 10.1097/BRS.0b013e318197f013

Figure 1.

Figure 1

Mechanical sensitivity of the hindpaw ipsilateral (left panels) and contralateral (right panels) to DRG exposure are shown as the number of paw withdrawals per 10 applications of a 10 g (top panels) and 2 g (bottom panels) von Frey filament. Data are presented as mean + standard deviation for n = 4 animals per group. Response analysis via a generalized linear model revealed a prominent heightened ipsilateral limb sensitivity to the 10 g test in the NP-treated group relative to sham controls (p < 0.05). Note the trend toward decreased mechanical sensitivity in the contralateral limb ofNP-treated animals compared with the sham animals at 1 week, though this resolved at subsequent time points.