Table 2.

Akt, receptor tyrosine kinase (RTK) and Stat signal pathway inhibitors

Agent(s)	Target protein	Reference
PI 103	PI3K/mTOR	[37]
SF1126 (LY294002-prodrug)	PI3K	[38]
Perifosine, PX-866	Akt	[22]
CMEP	Akt	[39]
Temsirolimus (CCI-779)	mTOR	[40]
Everolimus (RAD001)	mTOR	[40]
Deforolimus (AP23573)	mTOR	[41]
XL765	P13K/mTOR	[42]
SB216763, DW1/2	GSK3β	[43]
Imatinib, dasatinib, sunitinib, erlotinib	RTKs	[44]
Dasatinib	Src	[45]
S31-M2001	Stat3	[46]
SUI1274	c-Met/HGF	[24, 47]