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Targeting anti-apoptotic proteins
| Agent | Target protein(s) | Reference |
| Oblimersen (G3139) | Bcl-2 (specific) | [66] |
| YM155 | Survivin | [67] |
| ABT-737 (ABT-263) | BH3-mimetic (inhibits Bcl-2 group: Bcl-2, Bcl-XL, Bcl-W, not Mcl-1) | [68–70] |
| Gossypol (AT-101) | BH3-mimetic (inhibits Bcl-2 group) | [71] |
| Obatoclax (GX015-070) | BH3-mimetic (inhibits Bcl-2 group) | [72] |
| TW37 | Bim-mimetic (inhibits Bcl-2 group) | [73] |
| Smac mimetic | Inhibitor of IAP1,2, XIAP | [74] |
