Figure 5.

Annotated transcripts upregulated during prion disease and unrelated to cuprizone-induced neuroinflammation. Of the seventeen transcripts that increased in expression over the course of prion disease and remained unchanged during cuprizone treatment, fourteen were found to be annotated. The log₂ transformed expression ratios versus control are shown here for ease in visualization, allowing gene expression to be centered on zero. The shaded region represents non-significant, unchanging transcript levels. Unchanging was classified as |0.0-0.3| log₂ transformed expression ratio versus control.