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Examples of raw images and segmentation into GM, WM and CSF. a Example of high resolution T1-weighted image in sagittal view. b Typical multifocal white matter lesions, apparent as hyperintense areas on a FLAIR image of a study patient. c–e Exemplary axial slice of GM, WM and CSF of a patient after segmentation and spatial normalization. All maps were corrected for erronous inclusion of non-brain and non-CSF areas by applying a mask as overlaid in (e)
