Table 1.
GO term ID | GO term description | Number of genes in GO terma | Number of genes affectedb | p-value | FDR adjusted p-valuec |
Biological Process | |||||
GO:0051017 | actin filament bundle formation | 6 | 2 | 0.002 | 0.047 |
GO:0006996 | organelle organization and biogenesis | 3 | 2 | 0.002 | 0.047 |
GO:0015816 | glycine transport | 2 | 1 | 0.003 | 0.047 |
GO:0016042 | lipid catabolic process | 7 | 6 | 0.003 | 0.047 |
GO:0009113 | purine base biosynthetic proces | 4 | 2 | 0.003 | 0.047 |
Molecular function | |||||
GO:0019976 | interleukin-2 binding | 2 | 2 | 0.002 | 0.040 |
GO:0015187 | glycine transmembrane transporter activity | 2 | 1 | 0.003 | 0.040 |
GO:0031013 | troponin I binding | 2 | 1 | 0.003 | 0.040 |
GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine.... | 2 | 2 | 0.003 | 0.040 |
GO:0004438 | phosphatidylinositol-3-phosphatase activity | 2 | 2 | 0.003 | 0.040 |
Cellular component | |||||
GO:0001726 | ruffle | 18 | 9 | 0.003 | 0.034 |
GO:0005719 | nuclear euchromatin | 2 | 1 | 0.003 | 0.034 |
GO:0005884 | actin filament | 12 | 6 | 0.003 | 0.034 |
GO:0000307 | cyclin-dependent protein kinase... | 5 | 3 | 0.004 | 0.034 |
GO:0016529 | sarcoplasmic reticulum | 4 | 3 | 0.004 | 0.034 |
a Number of genes within each GO term.
b Genes differentially expressed with z-score > 2.0
c The p-values were adjusted for multiple hypotheses testing with Benjamini and Hochberg to control the false discovery rate (FDR).