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. 2009 Jul 29;4(7):e6430. doi: 10.1371/journal.pone.0006430

Figure 3. Akt hyper-phosphorylation does not appear to be related to increased IR-β, PI3K-p85, and PDK1 protein levels.

Figure 3

A. IR-β and PI3K-p85 protein in 6-, 27-, 33-month control (33C) and acetaminophen-treated (33T) rats were determined by immunoblotting. B. PDK1 total protein and phosphorylation of PDK1 at Ser241 as determined by immunoblotting. Data are mean±SE (n = 4–6). abc: Groups without the same letter are significantly different (P<0.05).