Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
MSCs protect transplanted allogeneic islets by creating an immunosuppressive microenvironment. MMP-2 and -9 produced by MSCs suppress T-cell responses by cleaving the high-affinity growth factor receptor CD25 (the α-chain of the IL-2 receptor) from the surface of infiltrating T-lymphocytes.
