. Author manuscript; available in PMC: 2010 Jan 1.

Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2009 Jan 6;80(1):57–64. doi: 10.1016/j.plefa.2008.11.004

Table 2.

Statistical Parametric Mapping of Correlations Between Plasma Polyunsaturated Fatty Acid Levels and Regional Cerebral Glucose Metabolism.

rCMRglu Analysis	Cluster- level P_corrected	Cluster Extent (voxels)		Anatomic Locations **Cluster Maxima	Brodmann Areas
Positively correlated with AA%	<0.001	10,402	Right	Precentral Gyrus**	6, 44
			“	Superior Temporal Gyrus	13, 22, 42
			“	Postcentral Gyrus	1
			“	Inferior Temporal Gyrus	20
			“	Insula	13
			“	Inferior Parietal Lobule	40
			“	Posterior Cingulate	29, 30
			“	Inferior Frontal Gyrus	11, 47
			“	Middle Temporal Gyrus	21
			“	Occipital Lobe, Lingual Gyrus	19
			“	Claustrum
			“	Precuneus	31
			Left	Cerebellum, Posterior Lobe, Declive, Uvula
			“	Cerebellum, Anterior Lobe, Culmen
			Right	Cerebellum, Posterior Lobe, Declive, Tuber
			“	Cerebellum, Anterior Lobe, Culmen

	0.050	1,939	Left	Superior Temporal Gyrus**	22
			“	Middle Temporal Gyrus	21
				Claustrum

Positively correlated with DHA%	0.033	2,137	Right	Precentral Gyrus**,	6
			“	Superior Temporal Gyrus	13, 22, 42
			“	Inferior Parietal Lobule	40

Negatively correlated with DHA%	< 0.001	4,957	Left	Cingulate Gyrus**,	24, 32
			“	Middle Frontal Gyrus	10, 11
			“	Inferior Frontal Gyrus	47
			“	Superior Frontal Gyrus	8

Abbreviations: rCMRglu, regional cerebral rate of glucose metabolism; DHA% and AA%, docosahexaenoate and arachidonate, respectively, as a percentage of total phospholipid fatty acids; p_corrected, p values after Statistical Parametric Analysis (SPM2) correction for multiple comparisons.