Table 3.
CSF diagnostic statistics to distinguish patients with a clinical diagnosis of AD from cognitively normal control subjects
| Biomarker | Cutoff | Specificity | Sensitivity | PPV | Overall Accuracy | PLR |
|---|---|---|---|---|---|---|
| t-tau | 404 | 90% | 69% | 96% | 73% | 7.0 |
| p-tau181 | 77 | 90% | 54.4% | 91% | 66% | 5.2 |
| β-amyloid 42 | 201 | 90% | 26% | 88% | 43% | 2.8 |
NOTE. All cutoff values expressed as pg/ml CSF.