Table 2.
Liver stiffness measurements applicability
Position, operator and quality criteria | Applicability (%) | Presumed fibrosis stages among applicable patients F0F1/F2/F3/F4 n (%)c |
Reference position | 306/442 (69)a | 167 (55)/59 (19)/51 (17)/29 (9)d |
Operator 1 | 208/329 (63) | 117 (56)/40 (19)/32 (15)/19 (9) |
Valid10 | 312/329 (95) | |
SR60 | 300/329 (91) | |
IQR30 | 220/329 (67) | |
Operator 2 | 98/113 (87) | 50 (51)/19 (19)/19 (19)/10 (10) |
Valid10 | 113/113 (100) | |
SR60 | 113/113 (100) | |
IQR30 | 98/113 (87) | |
Anterior position | 357/442 (81)a | 223 (62)/52 (15)/49 (14)/33 (9)d |
Operator 1 | 255/329 (78) | 166 (65)/34 (13)/31 (12)/24 (9) |
Valid10 | 300/329 (91) | |
SR60 | 296/329 (90) | |
IQR30 | 271/329 (82)b | |
Operator 2 | 102/113 (90) | 57 (56)/18 (18)/18 (18)/9 (9) |
Valid10 | 111/113 (98) | |
SR60 | 111/113 (98) | |
IQR30 | 103/113 (91)b | |
Lower position | 302/442 (68)a | 170 (56)/49 (16)/47 (16)/36 (12) |
Operator 1 | 224/329 (68) | 126 (56)/36 (16)/36 (16)/26 (12) |
Valid10 | 299/329 (91) | |
SR60 | 291/329 (88) | |
IQR30 | 240/329 (73)b | |
Operator 2 | 78/113 (69) | 44 (56)/13 (17)/11 (14)/10 (13) |
Valid10 | 96/113 (85) | |
SR60 | 94/113 (83) | |
IQR30 | 86/113 (76)b |
Applicability of the anterior position was significantly higher than that of the reference and the lower positions (both P = 0.0001);
IQR30 was obtained more frequently with the anterior position than with the reference and lower positions for operator 1 (82% vs 67% P < 0.0001; 82% vs 73% P = 0.004) and for operator 2 (91% vs 87% P = 0.40; 91% vs 76% P = 0.004);
Presumed fibrosis stage (METAVIR scoring system) using 7.7 kPa for F2, 8.8 kPa for F3 and 14.5 kPa for F4;
Presumed prevalence of non-advanced fibrosis was lower using the reference position than the anterior position (P = 0.04).