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. Author manuscript; available in PMC: 2009 Jul 20.
Published in final edited form as: Genet Epidemiol. 2005 Dec;29(4):336–352. doi: 10.1002/gepi.20095

Figure 7.

Figure 7

Efficiency of htSNP selection for a genuinely LD-based haplotype block structure vs. an arbitrarily-defined, non-LD-based pseudo-block structure. The x-axis denotes different parameter settings and the y-axis denotes the average number of htSNPs in the five studied blocks (blocks 4, 5 ,6, 8, and 9 in the UK Graves’ disease dataset). shaded bars, considering haplotype blocks; open bars, ignoring haplotype blocks; 1,000 simulations were conducted for each set of parameters. N, size of developing panel (in terms of number of chromosomes); and ϕ, haplotype diversity coverage. (A) results using E criterion; (B) results using H criterion.