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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2009 Jul 7;8(7):1799–1807. doi: 10.1158/1535-7163.MCT-09-0055

Figure 5. Effects of atorvastatin on phospho-S6 and GTP-RhoA levels in healthy tissues of Tsc2+/- mice.

Figure 5

Imunoblots of whole tissue lysates from lung are shown. Levels of phospho-T421/4-S6 kinase (pS6K), phospho-S235/6-S6 (pS6), total S6, GTP-RhoA and total RhoA were compared in vehicle control mice and those treated with atorvastatin for 6 months. Densitometric evaluation of the indicated proteins was calculated and expressed as fold difference of levels in atorvastatin (Atorv) treated mice compared to vehicle controls (Ctrl). Significance (p > 0.05) is indicated by *. These images are cropped and full length blots shown in Figure 5 can be viewed in supplemental Figure 3S.