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. Author manuscript; available in PMC: 2009 Jul 20.
Published in final edited form as: Radiat Res. 2009 May;171(5):596–605. doi: 10.1667/RR1632.1

FIG. 9.

FIG. 9

Effect of GT3 and/or mevalonate on circulating markers of endothelial dysfunction 8.5 Gy TBI induced a significant decrease in circulating E-selectin (panel A), MMP9 (panel B), VCAM (panel C) and ICAM (panel D) levels. At 14 days, E-selectin (P = 0.006), MMP9 (P = 0.006) and VCAM (P = 0.02) levels approached baseline values in GT3-treated animals while they were still severely reduced in mice treated with vehicle and mevalonate alone. There was no difference in ICAM levels among the treatment groups.