TABLE 1.
Distribution of demographic, gynecological, sexual behavior, and HPV characteristics for oncogenic HPV DNA positive women with negative, CIN1, and ≥CIN2-3 histology.
| HPV+, Negative Histology (n=152) | HPV+, CIN1 Histology (n=133) | p* | HPV+, ≥CIN2-3 Histology (n=173) | p* | |
|---|---|---|---|---|---|
| Characteristic | No. (%) | No. (%) | No. (%) | ||
| Age (years) | 0.10 | 0.88 | |||
| 18–19 | 23 (15) | 34 (26) | 24 (14) | ||
| 20–24 | 74 (49) | 64 (48) | 79 (46) | ||
| 25–29 | 37 (24) | 25 (19) | 46 (26) | ||
| 30–50 | 18 (12) | 10 (7) | 24 (14) | ||
| Race/Ethnicity | 0.36 | 0.47 | |||
| White | 99 (65) | 97 (73) | 123 (71) | ||
| Black | 20 (13) | 14 (10) | 21 (12) | ||
| Other | 33 (22) | 22 (17) | 29 (17) | ||
| Education | 0.86 | 0.34 | |||
| <12th grade | 17 (11) | 14 (11) | 14 (8) | ||
| ≥12th grade | 135 (89) | 119 (89) | 159 (92) | ||
| Ever Had a Cytologic Test Prior to Study | 0.02 | 0.03 | |||
| No | 1 (1) | 7 (5) | 8 (5) | ||
| Yes | 151 (99) | 126 (95) | 165 (95) | ||
| History of Abnormal Cytology‡ | 0.81 | <0.001 | |||
| No | 98 (65) | 80 (63) | 66 (40) | ||
| Yes | 53 (35) | 46 (37) | 99 (60) | ||
| Parity | 0.06 | 0.15 | |||
| 0 | 100 (66) | 87 (65) | 96 (55) | ||
| 1 | 29 (19) | 36 (27) | 46 (27) | ||
| ≥2 | 23 (15) | 10 (8) | 31 (18) | ||
| Age at First Sexual Intercourse (years) | 0.23 | 0.50 | |||
| ≤13 | 20 (13) | 21 (16) | 19 (12) | ||
| 14–17 | 104 (70) | 79 (60) | 108 (66) | ||
| ≥18 | 26 (17) | 32 (24) | 37 (22) | ||
| Lifetime Number of Male Partners§ | 0.13 | 0.48 | |||
| 1 | 5 (3) | 12 (9) | 5 (3) | ||
| 2–4 | 37 (25) | 29 (22) | 32 (19) | ||
| 5–14 | 76 (50) | 71 (53) | 101 (58) | ||
| ≥15 | 33 (22) | 21 (16) | 35 (20) | ||
| Cigarette Smoking Status | 0.11 | 0.35 | |||
| Never smoker | 53 (35) | 34 (25) | 50 (29) | ||
| Former smoker | 26 (17) | 34 (26) | 39 (22) | ||
| Current smoker | 73 (48) | 65 (49) | 84 (49) | ||
| Number of Oncogenic HPV Types at Colposcopy-Biopsy | 0.04 | <0.001 | |||
| 1 | 122 (80) | 93 (70) | 108 (62) | ||
| 2+ | 30 (20) | 40 (30) | 65 (38) | ||
| Type-specific Oncogenic HPV Repeat Positivity|| | 0.01 | <0.001 | |||
| No | 56 (38) | 31 (23) | 20 (12) | ||
| Yes | 92 (62) | 102 (77) | 151 (88) | ||
p value (two-sided) for Pearson’s chi-square test of the null hypothesis that the CIN1 histology group and ≥CIN2-3 histology group are different than the negative histology group with respect to the distribution of the listed characteristics.
Among those who had at least one cytologic test and does not include cytologic result from study screening visit.
Two women in the negative histology group, one woman in the CIN1 histology group, and nine women in the ≥CIN2-3 histology group were missing information on age at first sexual intercourse.
One woman in the negative histology group was missing information on lifetime number of male partners.
Four women in the negative histology group and two women in the ≥CIN2-3 histology group had insufficient PCR results from screening and therefore type-specific oncogenic HPV repeat positivity could not be determined.