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. 2009 Apr 29;330(2):476–486. doi: 10.1124/jpet.108.150037

Fig. 3.

Fig. 3.

Top, effects of cumulative doses of cocaine in separate groups of rats treated with saline (saline), 0.3 mg/kg naltrexone (0.3 NTX), and 3.0 mg/kg naltrexone (3.0 NTX). Bottom, effects of cumulative doses of cocaine in separate groups of rats treated with saline (saline), 10 mg/kg nor-binaltorphimine (10 NBNI), and 1.0 mg/kg naltrindole (1.0 NTI). Left, locomotor activity expressed as a percentage of saline control values. Right, AUC estimates for each group. Vertical lines, S.E.; where not indicated, the S.E. fell within the data point.