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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Nucl Med Biol. 2009 Jan;36(1):3–10. doi: 10.1016/j.nucmedbio.2008.10.003

Table 2.

Affinity of competing ligands at human and rat A3ARs expressed in CHO cells using [76Br]MRS5147 6.

Ligand Human Ki, nM Rat Ki, nM
MRS1220 1.1 ± 0.3 >10,000
MRS1523 120 ± 17 2830 ± 520
6 MRS5147 0.62 ± 0.16 5.2 ± 1.8
NECA 38 ± 12 126 ± 31

MRS 1220: N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]benzeneacetamide; MRS1523: 5-propyl-2-ethyl-4-propyl-3-(ethylsulfanylcarbonyl)-6-phenylpyridine-5-carboxylate;

NECA: adenosine-5′-N-ethyluronamide.