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. Author manuscript; available in PMC: 2009 Jul 20.
Published in final edited form as: Neuropsychologia. 2007 Dec 14;46(6):1597–1612. doi: 10.1016/j.neuropsychologia.2007.10.026

Figure 7.

Figure 7

Using a single surface template and an optical flow registration approach for ventricular segmentation, Carmichael et al. (102) compared the ventricular shape differences between MCI, AD and cognitively normal subjects. The figure shows the average thickness, percent deficit and significance maps of the three comparisons – cognitively normal subjects vs. MCI (top row), cognitively normal subjects vs. AD (bottom row) and MCI vs. AD (middle row). As expected, progressive ventricular expansion was evident - MCI subjects had intermediate and AD subjects largest ventricles.