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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Environ Microbiol. 2009 Jan 23;11(5):1242–1253. doi: 10.1111/j.1462-2920.2008.01852.x

Figure 3. Reversible suppression of multiple pro-inflammatory cytokines in human PBMCs stimulated with CSE-treated P. gingivalis.

Figure 3

Figure 3

Figure 3

Primary human PBMCs (0.5 × 106) were stimulated for 20 h with GAM cultured P. gingivalis; CSE-treated P. gingivalis; or P. gingivalis cells that were first grown in GAM-CSE for two passages then reconditioned in untreaαted GAM for 2 passages (107 P. gingivalis cells). PBMCs stimulated with reconditioned P. gingivalis produced levels of TNF-α that were similar to PBMCs that were stimulated with bacteria from control cultures (not exposed to CSE). Error bars represent the mean (s.d.) of 3 experiments.

* Indicates statistical significance at p < 0.05.

** Indicates statistical significance at p < 0.01.